Clinical trials for carbon-ion radiotherapy in Japan
نویسندگان
چکیده
منابع مشابه
Carbon-ion radiotherapy—basic and clinical studies
Radiotherapy using charged and/or high-LET particles has a long history, starting with proton beams. In vitro data clarify that RBE (Relative Biological Effectiveness) increases with LET up to approximately 150 keV/μm for carbon-12 and neon-20 ions. In vivo studies show that tumor control probabilities after single doses of gamma rays shift to higher doses when tumors were irradiated with 5-fra...
متن کاملClinical advantages of carbon-ion radiotherapy
Carbon-ion radiotherapy (C-ion RT) possesses physical and biological advantages. It was started at NIRS in 1994 using the Heavy Ion Medical Accelerator in Chiba (HIMAC); since then more than 50 protocol studies have been conducted on almost 4000 patients with a variety of tumors. Clinical experiences have demonstrated that C-ion RT is effective in such regions as the head and neck, skull base, ...
متن کاملCarbon ion radiotherapy in Japan: an assessment of 20 years of clinical experience.
Charged particle therapy is generally regarded as cutting-edge technology in oncology. Many proton therapy centres are active in the USA, Europe, and Asia, but only a few centres use heavy ions, even though these ions are much more effective than x-rays owing to the special radiobiological properties of densely ionising radiation. The National Institute of Radiological Sciences (NIRS) Chiba, Ja...
متن کاملClinical trial of carbon ion radiotherapy for gynecological melanoma
Carbon ion radiotherapy (C-ion RT) is an advanced modality for treating malignant melanoma. After we treated our first case of gynecological melanoma using C-ion RT in November 2004, we decided to conduct a clinical trial to evaluate its usefulness for the treatment of gynecological melanoma. The eligibility criteria for enrollment in this study were histologically proven malignant melanoma of ...
متن کاملA Review of Update Clinical Results of Carbon Ion Radiotherapy
Among various types of ion species, carbon ions are considered to have the most balanced, optimal properties in terms of possessing physically and biologically effective dose localization in the body. This is due to the fact that when compared with photon beams, carbon ion beams offer improved dose distribution, leading to the concentration of the sufficient dose within a target volume while mi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Radiotherapy and Oncology
سال: 2016
ISSN: 0167-8140
DOI: 10.1016/s0167-8140(16)30215-8